
The first two human Phase II trials of AIMSPRO have been designed to test two potential aspects of the medication's mechanism of action (ClinicalTrials.gov). The scleroderma (diffuse sclerosis) study (at the Royal Free Hospital, London) will examine the safety and tolerance of AIMSPRO as a general anti-inflammatory agent in the later phase of this disabling chronic rheumatological disorder. 20 patients are being randomised to receive either AIMSPRO or placebo under double-blind conditions, over a period of 6 months.
In a study of AIMSPRO as a potential treatment of bladder dysfunction in secondary progressive multiple sclerosis the hypothesised ability of the medication to reduce sodium channel triggering voltages is also being tested, using a double-blind "cross-over" design.
Colleagues wishing to discuss these, or other potential studies, are welcome to contact Dr. Bryan Youl, Clinical Director, via Daval or by phoning +44 7793 526 096.
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5th Nov 2009 AIMSPRO receives US orphan-drug designation for ALS |
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29th Sep 2009 Ceremben Permit Approved |
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22nd Jul 2009 Patent granted by the OAPI |